Table 2. Subgroup analyses for the pooled results of differences in serum IL-6 levels between SLE patients and healthy controls.
Variables | No. of studies | Pooled SMD (95% CI) | p-value | Heterogeneity | |
---|---|---|---|---|---|
I2 (%) | p-value | ||||
[1] Age | |||||
Adult | 10 | 2.257 (1.054-3.46) | <0.01 | 97.5 | <0.01 |
Child | 3 | 1.861 (0.499-3.224) | <0.01 | 94.4 | <0.01 |
[2] Region | |||||
Non-Asia | 6 | 0.757 (0.24-1.275) | <0.01 | 81.7 | <0.01 |
Asia | 7 | 3.508 (1.662-5.354) | <0.01 | 98.3 | <0.01 |
[3] Measuring methods | |||||
ELISA | 9 | 2.914 (1.37-4.458) | <0.01 | 88.6 | <0.01 |
Other methods | 4 | 0.691 (0.181-1.201) | <0.01 | 37.5 | 0.2 |