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. 2020 Oct 5;75:e1801. doi: 10.6061/clinics/2020/e1801

Table 2. Subgroup analyses for the pooled results of differences in serum IL-6 levels between SLE patients and healthy controls.

Variables No. of studies Pooled SMD (95% CI) p-value Heterogeneity
I2 (%) p-value
[1] Age
    Adult 10 2.257 (1.054-3.46) <0.01 97.5 <0.01
    Child 3 1.861 (0.499-3.224) <0.01 94.4 <0.01
[2] Region
    Non-Asia 6 0.757 (0.24-1.275) <0.01 81.7 <0.01
    Asia 7 3.508 (1.662-5.354) <0.01 98.3 <0.01
[3] Measuring methods
    ELISA 9 2.914 (1.37-4.458) <0.01 88.6 <0.01
    Other methods 4 0.691 (0.181-1.201) <0.01 37.5 0.2