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. 2020 Sep 23;33(6):e23504. doi: 10.1002/ajhb.23504

FIGURE 3.

FIGURE 3

India shows a less severe COVID‐19 likely because it has more trained hosts due to endemic exposure to intracellular pathogens. A, A simplistic mortality curve model based on data for COVID‐19 considering the nature of the hosts that are succumbing to infections (Huang et al., 2020) is drawn. Based on the data from He et al. (2020), a presymptomatic transmission is assumed (a 100% transmission is an assumption in the model, even though He et al. (2020) have shown it as 44%). The resistance of the hosts increases over time in the mortality curve as shown. B, The curve of daily deaths for the United States and India. The data for each country begins from the day it had its first death and goes till the next 134 days. The 134 days was chosen since India had passed that many days from the day of its first death due to COVID‐19, till Jul 24, 2020. C, Trained immunity could also be due to exposure to endemic intracellular pathogens. The Indian hosts get a constant exposure to infections from M. tuberculosis, arthropod‐borne RNA viruses, and protozoan parasites and develops a trained immune system that protects them from a severe disease from a new but related pathogen like SARS‐CoV‐2