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Comparison of receiver operating curves (ROC) for IGF1, IGF2, and IGFBP2as predictors of pulmonary arterial hypertension for 127 subjects from the JHPH cohort and 128 healthy control subjects. The AUC for IGFBP2 is 0.76, 95% confidence interval [CI] 0.698–0.808, p < 0.0001; AUC for IGF1 is 0.52, 95% confidence interval [CI] 0.455–0.583, p = 0.61; and AUC for IGF2 is 0.50, 95% confidence interval [CI] 0.438–0.566, p = 0.96
