Table 1.
Transcription factor enrichment in 1,819 PEO1-OR associated differentially regulated genes.
| Rank | Transcription Factor | # Genes in Gene Set | # Genes in Overlap | % of Overlap | p-value | FDR q-value |
|---|---|---|---|---|---|---|
| 1 | TCF3 | 2485 | 339 | 13.64% | 8.48E-100 | 5.22E-97 |
| 2 | SP1 | 2940 | 361 | 12.28% | 3.07E-93 | 9.44E-91 |
| 3 | MAZ | 2274 | 293 | 12.88% | 1.99E-79 | 4.09E-77 |
| 4 | LEF1 | 1972 | 255 | 12.93% | 6.04E-69 | 9.29E-67 |
| 5 | UNKNOWN | 1890 | 244 | 12.91% | 1.04E-65 | 1.28E-63 |
| 6 | NFAT | 1896 | 221 | 11.66% | 1.31E-51 | 1.34E-49 |
| 7 | AP4 | 1524 | 189 | 12.40% | 6.21E-48 | 5.45E-46 |
| 8 | FOXO4 | 2061 | 223 | 10.82% | 1.15E-46 | 8.84E-45 |
| 9 | TATA1 | 1296 | 158 | 12.19% | 4.07E-39 | 2.78E-37 |
| 10 | AP1 | 1121 | 142 | 12.67% | 5.00E-37 | 3.08E-35 |