FIGURE 2.
Expression of RAGE in different tissues, mostly expressed in AT2 (alveolar type 2 pneumocyte) cells in lung. A, Values and correlations of RAGE gene expression in many organs, mostly in the lung (dark arrow). Adapted from https://gtexportal.org/. 146 , 147 B, Data set Genes collected from integrated single‐cell RNA‐Seq analysis of patients with pulmonary fibrosis. RAGE (C3) detectable expression is far more pronounced in AT2 cells compared to other important proteins in SARS‐CoV‐2 infection process, such as ACE2 (C1) and TMPRSS2 (C2). Adapted from https://www.nupulmonary.org/ 148