Table 1.

Inclusion and exclusion criteria

Inclusion criteria	Exclusion criteria
Diagnosis of cystic fibrosis as confirmed by standard criteria52	Evidence of pulmonary exacerbation within 3 weeks prior to screening
Sixteen years of age or older	Any change in a chronic treatment/prophylaxis for CF or CF-related condition within 4 weeks of visit
	Current haemoptysis
	Dependency on positive pressure support with airway clearance technique
	Previous history of spontaneous rib fracture
	Pregnancy
	Inability to give consent for treatment or measurement
	Enrolment in another interventional study
	Dependent on non-invasive ventilation or oxygen therapy at rest