Table 3.

Primary and secondary outcome measures

Primary outcome measures

Secondary outcome measures

Forced expiratory volume in 1 s Sputum wet weight expectorated during treatment End expiratory lung impedance derived from EIT LCI2.5 derived from MBW R5–R20 derived from IOS

Forced vital capacity (FVC), forced expiratory flow at 25% of FVC, forced expiratory flow at 50% of FVC, forced expiratory flow at 75% of FVC, slow vital capacity derived from spirometry Oxygen saturation measurements during treatment Patient feedback questionnaire Regions of interest % derived from EIT Functional residual capacity, LCI5, Scond, Sacin, washout time, number of washout breaths, M1M0, M2M0 derived from MBW R5, R20, X, Fres derived from IOS

EIT, electrical impedance tomography; IOS, impulse oscillometry; LCI 2.5, Lung Clearance Index; MBW, multiple breath washout.