Table 1.
Demographic, clinical, and laboratory findings of patients with and without myocardial injury on admission
| Total (n = 353) | Without myocardial injury (n = 274) | With myocardial injury (n = 79) | P value | |
|---|---|---|---|---|
| Demographic and clinical characteristics | ||||
| Age (years) | 60.47 ± 10.05 | 57.65 ± 14.68 | 70.25 ± 11.96 | <0.01 |
| Sex, male (%) | 186 (52.7) | 136 (49.6) | 50 (63.3) | 0.03 |
| Exposure history (%) | 218 (61.8) | 165 (60.2) | 53 (67.1) | 0.27 |
| Co‐morbidity | ||||
| Hypertension (%) | 129 (36.5) | 87 (31.8) | 42 (53.2) | <0.01 |
| Diabetes (%) | 67 (19.0) | 49 (17.9) | 18 (22.8) | 0.33 |
| Coronary heart disease (%) | 40 (11.3) | 24 (8.8) | 16 (20.3) | 0.01 |
| Chronic obstructive lung disease (%) | 26 (7.4) | 18 (6.6) | 8 (10.1) | 0.29 |
| Chronic kidney disease (%) | 13 (3.7) | 3 (1.1) | 10 (12.7) | <0.01 |
| Carcinoma (%) | 11 (3.1) | 9 (3.3) | 2 (2.5) | 0.73 |
| Stroke (%) | 13 (3.7) | 10 (3.6) | 3 (3.8) | 0.95 |
| Symptom | ||||
| Fever (temperature ≥37.3°C) (%) | 271 (76.8) | 211 (77.0) | 60 (75.9) | 0.84 |
| Cough (%) | 288 (81.6) | 219 (79.9) | 69 (87.3) | 0.13 |
| Sputum (%) | 185 (52.4) | 141 (51.5) | 44 (55.7) | 0.51 |
| Dyspnoea (%) | 129 (36.5) | 90 (32.8) | 39 (49.4) | 0.01 |
| Pharyngalgia (%) | 45 (12.7) | 32 (11.7) | 13 (16.5) | 0.26 |
| Headache (%) | 51 (14.4) | 40 (14.6) | 11 (13.9) | 0.88 |
| Myalgia (%) | 71 (20.1) | 53 (19.3) | 18 (22.8) | 0.5 |
| Fatigue (%) | 135 (38.2) | 104 (38.0) | 31 (39.2) | 0.84 |
| Chest pain (%) | 63 (17.8) | 44 (16.1) | 19 (24.1) | 0.1 |
| Chest distress (%) | 144 (40.8) | 102 (37.2) | 42 (53.2) | 0.01 |
| Diarrhoea (%) | 81 (22.9) | 58 (21.2) | 23 (29.1) | 0.14 |
| Nausea or vomiting (%) | 49 (13.9) | 37 (13.5) | 12 (15.2) | 0.7 |
| CURB‐65 score | <0.01 | |||
| 0–1 (%) | 220 (62.3) | 205 (74.8) | 15 (19.0) | |
| 2 (%) | 77 (21.8) | 58 (21.2) | 19 (24.1) | |
| 3–5 (%) | 56 (15.9) | 11 (4.0) | 45 (56.9) | |
| Disease severity status | <0.01 | |||
| General (%) | 247 (70.0) | 229 (83.6) | 18 (22.8) | |
| Severe (%) | 56 (15.9) | 40 (14.6) | 16 (20.3) | |
| Critical (%) | 50 (14.1) | 5 (1.8) | 45 (57.0) | |
| Physical examination | ||||
| Systolic blood pressure (mmHg) | 130.86 ± 18.55 | 129.86 ± 17.97 | 134.32 ± 20.17 | 0.06 |
| Diastolic blood pressure (mmHg) | 79.11 ± 12.24 | 78.85 ± 11.77 | 79.99 ± 13.77 | 0.47 |
| Heart rate (b.p.m.) | 88.19 ± 14.29 | 86.76 ± 14.19 | 93.16 ± 13.61 | <0.01 |
| Respiratory rate (breaths per minute) | 20.96 ± 4.62 | 20.60 ± 4.31 | 22.20 ± 5.40 | 0.02 |
| Temperature (°C) | 36.80 ± 0.74 | 36.75 ± 0.71 | 36.96 ± 0.81 | 0.04 |
| Minimum SpO2 (%) | 90.39 ± 12.09 | 93.99 ± 5.86 | 77.78 ± 18.34 | <0.01 |
| Laboratory findings | ||||
| White blood cell count (× 109/L) | 6.40 ± 3.04 | 5.79 ± 1.99 | 8.56 ± 4.69 | <0.01 |
| Lymphocyte count (× 109/L) | 1.30 ± 0.57 | 1.42 ± 0.52 | 0.85 ± 0.49 | <0.01 |
| Neutrophil count (× 109/L) | 4.50 ± 3.08 | 3.75 ± 1.85 | 7.12 ± 4.71 | <0.01 |
| Minimum lymphocyte count (× 109/L) | 1.18 ± 0.55 | 1.33 ± 0.48 | 0.66 ± 0.44 | <0.01 |
| Maximum neutrophil/lymphocyte | 8.48 ± 15.38 | 3.75 ± 3.58 | 25.12 ± 25.96 | <0.01 |
| Monocyte count (× 109/L) | 0.62 ± 1.11 | 0.62 ± 1.15 | 0.62 ± 1.00 | 0.99 |
| Haemoglobin (g/L) | 126.59 ± 17.22 | 126.96 ± 15.31 | 125.29 ± 22.78 | 0.54 |
| Platelet count (× 109/L) | 250.89 ± 100.25 | 265.54 ± 91.74 | 199.32 ± 111.96 | <0.01 |
| Albumin (g/L) | 36.33 ± 5.22 | 37.56 ± 4.53 | 32.08 ± 5.22 | <0.01 |
| Alanine transaminase (U/L) | 55.73 ± 239.14 | 34.89 ± 34.44 | 127.87 ± 496.77 | <0.01 |
| Creatinine (μmol/L) | 90.07 ± 78.18 | 71.16 ± 18.79 | 155.42 ± 143.86 | <0.01 |
| Lactate dehydrogenase (U/L) | 338.54 ± 296.87 | 243.72 ± 84.14 | 655.05 ± 480.10 | <0.01 |
| High‐sensitivity cardiac troponin I (pg/mL) | 329.33 ± 3041.59 | 4.91 ± 4.12 | 1428.02 ± 6278.61 | <0.01 |
| Myoglobin (ng/mL) | 123.40 ± 246.35 | 43.30 ± 41.79 | 396.18 ± 408.17 | <0.01 |
| Creatine phosphokinase‐MB (ng/mL) | 1.87 ± 4.74 | 0.76 ± 0.78 | 5.62 ± 8.91 | <0.01 |
| N‐terminal pro‐brain natriuretic peptide (pg/mL) | 1727.72 ± 6878.03 | 125.24 ± 136.62 | 6913.51 ± 12914.95 | <0.01 |
| Prothrombin time (s) | 14.50 ± 5.26 | 13.59 ± 0.80 | 17.51 ± 10.35 | <0.01 |
| d‐dimer (μg/mL) | 3.80 ± 7.38 | 1.73 ± 5.07 | 10.80 ± 9.43 | <0.01 |
| High‐sensitivity C‐reactive protein (mg/L) | 43.62 ± 68.14 | 21.50 ± 37.54 | 120.22 ± 91.32 | <0.01 |
| IL‐1β (pg/mL) | 13.74 ± 69.43 | 8.31 ± 19.07 | 29.83 ± 133.89 | 0.01 |
| IL‐2R (U/mL) | 767.02 ± 788.73 | 490.81 ± 260.34 | 1585.79 ± 1176.23 | <0.01 |
| IL‐6 (pg/mL) | 189.38 ± 781.30 | 8.69 ± 20.74 | 728.22 ± 1438.00 | <0.01 |
| IL‐8 (pg/mL) | 102.87 ± 501.07 | 14.59 ± 28.17 | 364.57 ± 955.62 | <0.01 |
| TNF‐α (pg/mL) | 14.54 ± 36.95 | 7.76 ± 5.00 | 34.63 ± 69.73 | <0.01 |
IL, interleukin; SpO2, oxygen saturation; TNF, tumour necrosis factor.