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. 2020 Oct 14;93(3):1792–1795. doi: 10.1002/jmv.26554

Table 1.

Inactivation of SARS‐CoV‐2 and HCoV‐229E by ColdZyme® (CZ‐MD)

Virus Sample Input load log10TCID50 (mean)a Output load log10TCID50 (mean ± SD) log10 Reduction (mean) Percent inactivation
SARS‐CoV‐2, strain USA‐WA1/2020, BEI Resources NR‐52281 CZ‐MD 6.06 4.30 ± 0.21 1.76 98.3
Reference agent (2000 ppm NaOCl) ≤ 1.61 ≥4.45
Human coronavirus (HCoV), strain 229E, ATCC VR‐740 CZ‐MD 5.55 2.67 ± 0.13 2.88 99.9
Reference agent (2000 ppm NaOCl) ≤1.31 ≥4.24

Abbreviation: SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2; TCID50, 50% tissue culture infectious dose.

a

Mean of two experimental values.