Table 2.
HLA Class II epitope prediction
| SMM core | Peptides | HLA‐restriction | Percentile rank | |
|---|---|---|---|---|
| a | FELLHAPAT | LSFELLHAPATVCGP | HLA‐DRB1*01:01 | 0.03 |
| VLSFELLHAPATVCG | HLA‐DRB1*01:01 | 0.03 | ||
| VVLSFELLHAPATVC | HLA‐DRB1*01:01 | 0.03 | ||
| SFELLHAPATVCGPK | HLA‐DRB1*01:01 | 0.09 | ||
| VVVLSFELLHAPATV | HLA‐DRB1*01:01 | 0.09 | ||
| FELLHAPATVCGPKK | HLA‐DRB1*01:01 | 0.71 | ||
| b | VVVLSFELL | QPYRVVVLSFELLHA | HLA‐DPA1*03:01/DPB1*04:02 | 0.24 |
| PYRVVVLSFELLHAP | HLA‐DPA1*03:01/DPB1*04:02 | 0.25 | ||
| YRVVVLSFELLHAPA | HLA‐DPA1*03:01/DPB1*04:02 | 0.25 | ||
| PYRVVVLSFELLHAP | HLA‐DPA1*02:01/DPB1*01:01 | 0.3 | ||
| QPYRVVVLSFELLHA | HLA‐DPA1*02:01/DPB1*01:01 | 0.3 | ||
| YQPYRVVVLSFELLH | HLA‐DPA1*02:01/DPB1*01:01 | 0.3 | ||
| YRVVVLSFELLHAPA | HLA‐DPA1*02:01/DPB1*01:01 | 0.3 | ||
| PYRVVVLSFELLHAP | HLA‐DPA1*01:03/DPB1*02:01 | 0.36 | ||
| QPYRVVVLSFELLHA | HLA‐DPA1*01:03/DPB1*02:01 | 0.36 | ||
| YQPYRVVVLSFELLH | HLA‐DPA1*01:03/DPB1*02:01 | 0.36 | ||
| YRVVVLSFELLHAPA | HLA‐DPA1*01:03/DPB1*02:01 | 0.36 | ||
| RVVVLSFELLHAPAT | HLA‐DPA1*02:01/DPB1*01:01 | 0.63 | ||
| VVVLSFELLHAPATV | HLA‐DPA1*02:01/DPB1*01:01 | 0.68 | ||
| RVVVLSFELLHAPAT | HLA‐DPA1*03:01/DPB1*04:02 | 0.85 | ||
| YQPYRVVVLSFELLH | HLA‐DPA1*03:01/DPB1*04:02 | 2.2 | ||
| c | FLVLLPLVS | FVFLVLLPLVSSQCV | HLA‐DRB1*01:01 | 0.24 |
| MFVFLVLLPLVSSQC | HLA‐DRB1*01:01 | 0.24 | ||
| VFLVLLPLVSSQCVN | HLA‐DRB1*01:01 | 1.3 | ||
| FLVLLPLVSSQCVNL | HLA‐DRB1*01:01 | 1.8 | ||
| d | VLSFELLHA | RVVVLSFELLHAPAT | HLA‐DRB1*01:01 | 0.24 |
| e | GYQPYRVVV | GYQPYRVVVLSFELL | HLA‐DPA1*02:01/DPB1*01:01 | 0.3 |
| f | FGAGAALQI | SGWTFGAGAALQIPF | HLA‐DRB1*09:01 | 0.33 |
| TSGWTFGAGAALQIP | HLA‐DRB1*09:01 | 0.34 | ||
| GWTFGAGAALQIPFA | HLA‐DRB1*09:01 | 0.35 | ||
| WTFGAGAALQIPFAM | HLA‐DRB1*09:01 | 0.67 | ||
| WTFGAGAALQIPFAM | HLA‐DQA1*05:01/DQB1*03:01 | 1.6 | ||
| g | FVFLVLLPL | MFVFLVLLPLVSSQC | HLA‐DPA1*03:01/DPB1*04:02 | 0.34 |
| FVFLVLLPLVSSQCV | HLA‐DPA1*03:01/DPB1*04:02 | 0.36 | ||
| MFVFLVLLPLVSSQC | HLA‐DPA1*01:03/DPB1*02:01 | 5.2 | ||
| h | RVVVLSFEL | GYQPYRVVVLSFELL | HLA‐DPA1*01:03/DPB1*02:01 | 0.36 |
| GYQPYRVVVLSFELL | HLA‐DPA1*03:01/DPB1*04:02 | 6.2 | ||
| i | FTISVTTEI | AIPTNFTISVTTEIL | HLA‐DRB1*07:01 | 0.4 |
| PTNFTISVTTEILPV | HLA‐DRB1*07:01 | 0.51 | ||
| IPTNFTISVTTEILP | HLA‐DRB1*07:01 | 0.52 | ||
| TNFTISVTTEILPVS | HLA‐DRB1*07:01 | 0.52 | ||
| NFTISVTTEILPVSM | HLA‐DRB1*07:01 | 2.5 | ||
| FTISVTTEILPVSMT | HLA‐DRB1*07:01 | 2.6 | ||
| j | TNFTISVTT | IAIPTNFTISVTTEI | HLA‐DRB1*07:01 | 0.47 |
Abbreviation: HLA, human leukocyte antigen.