Figure 2.
IHC analysis of spleen, mesenteric lymph node and tumor tissue humanized NOG mice. Formalin-fixed and paraffin embedded tissue blocks where cut into slices of 4 µM and stained for PD-1, CD3 and CD8 (40x). H&E staining served to analyze tissue viability and morphology (40x). Scalebar: 50 µm. IHC, immunohistochemical; PD-1, programmed cell death protein-1.