. 2020 Oct 5;8(2):e001204. doi: 10.1136/jitc-2020-001204

Table 2.

Human DC and macrophage subsets and surface markers in different tissues

Tissue	DCs	Macrophages	References
Lung	cDC1: HLA-DR⁺, CD11c⁺, CADM1⁺, CD26⁺, CLA⁺, CD226⁺, CD49d^med, BDCA3⁺ cDC2/moDC: HLA-DR⁺, CD11c⁺, CLA⁺, CD49d^hi, CD2^med, BDCA1⁺, CD11b⁺, SIRPα⁺, CD1a⁺ pDC: HLA-DR⁺, CD49d⁺, CLA⁺, CD123⁺	Alveolar macrophage: SSC^hi, HLA-DR⁺, CD206⁺, CD14^lo, CD11c⁺, CD11b⁺, BDCA3⁺, CD64^med, CD43⁺ Interstitial macrophage 1: HLA-DR^lo, CD206⁺, CD36⁺ Interstitial macrophage 2: HLA-DR⁺, CD206⁺, CD36^lo	19 165–167
Kidney	cDC1: HLA-DR⁺, CD11c⁺, BDCA3⁺ cDC2/moDC: HLA-DR⁺, CD11c^lo, CD11b⁺, BDCA1⁺, DC-SIGN⁺ pDC: HLA-DR⁺, CD11b⁺, BDCA2⁺	Kidney macrophage 1: HLA-DR⁺, CD11b⁺, BDCA3⁺, DC-SIGN⁺ Kidney macrophage 2: CD14⁺, CD16^med, CD68⁺, 25F9⁺	86
Pancreas	cDC1: HLA-DR⁺, FLT3⁺, BDCA3⁺ cDC2: HLA-DR⁺, FLT3⁺, BDCA1⁺ pDC: BDCA-2⁺, CD123⁺	Pancreas TAM: HLA-DR^med/hi, CD163⁺, CD68⁺, CD206⁺, CD14⁺, CSF1R⁺	137 141 161 168
Liver	cDC1: HLA-DR⁺, CD14^lo, CD16^lo, CD11c^med, BDCA3⁺, CLEC9A⁺ cDC2: HLA-DR⁺, CD14^lo, CD16^lo, CD11c^hi, BDCA1⁺ pDC: HLA-DR⁺, CD14^lo, CD16^lo, CD11c^lo, CD123⁺	Kupffer cell: HLA-DR⁺, CD68⁺, CD16⁺, CD14^med, CX₃CR1⁺, CD163⁺, CD206^med	165 169–171
Ovary/ ascites	Myeloid DC/moDC: HLA-DR⁺, BDCA1⁺ pDC: HLA-DR⁺, CD4⁺, CD123⁺, BDCA2⁺	Peritoneal monocyte/macrophage: (1) HLA-DR⁺, CD14^hi, CD16^-; (2) HLA-DR⁺, CD14^hi, CD16⁺; (3) HLA-DR⁺, CD14^hi, CD16^hi	117 118 172 173
Breast	cDC1: HLA-DR⁺, CD11c⁺, BDCA3^hi, CLEC9A⁺, XCR1⁺, BTLA⁺ cDC2: HLA-DR⁺, CD11c⁺, CD11b⁺, BDCA1⁺, BDCA3^-/lo, SIRPα⁺ pDC: HLA-DR⁺, CD123⁺, CD11b⁺, SIRPα⁺, BTLA^-/lo	Breast TAM1: HLA-DR⁺, CSFR1⁺, CD68⁺, CD163⁺ Breast TAM2: HLA-DR⁺, CSFR1⁺, CD68⁺, CD163⁺, SIGLEC1⁺ Breast TAM3: HLA-DR⁺, CSFR1⁺, CD68⁺, SIGLEC1⁺	98 174

cDC, conventional dendritic cell; moDC, monocyte-derived dendritic cell; pDC, plasmacytoid dendritic cell; TAM, tumor-associated macrophage.