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. 2020 Jul 22;217(10):e20191761. doi: 10.1084/jem.20191761

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© 2020 Poholek et al.

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Figure 2. — STAT3 deletion reduces effector Th17 cell numbers in vivo. Th17^ΔSTAT3 and Th17^ctrl mice were immunized with MOG(35–55) in CFA to induce EAE. (A–E) At the indicated time points, live CD4⁺YFP⁺ cells were analyzed by flow cytometry in dLNs (A and B), blood (C), and the CNS (D and E) on indicated days after immunization. Data points show values for individual mice with mean ± SD, pooled from two to four experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001, one-way ANOVA (except C, Student’s t test).