Table 3.

Transcriptomic analyses: differential gene expression of coronavirus receptors/interactors in cancer versus normal tissues. ‘✓’ indicates a significant change in cancer versus healthy controls observed in the GEPIA2 database and ‘✓✓’ indicates significant change in cancer versus controls observed in the GEPIA2 database and validated in the GENT2 database. Empty cells indicate no significant difference observed in the GEPIA2 database. Significance threshold: P < 0.0001.

Cancer type (GEPIA2 database)	ACE2	TMPRSS2	CLEC4M	DPP4	TMPRSS11D
Adrenocortical carcinoma	–	–	–	–	–
Bladder urothelial carcinoma	–	–	–	–	–
Breast invasive carcinoma	–	✓✓	–	✓✓	–
Cervic squamous cell carcinoma/endocervical adenocarcinoma	–	–	–	–	–
Cholangiocarcinoma	✓	–	✓	–	–
Colon adenocarcinoma	✓✓	✓✓	–	–	–
Lymphoid neoplasm diffuse large B‐cell lymphoma	–	–	–	–	–
Esophageal carcinoma	–	✓	–	✓	✓
Glioblastoma multiforme	–	–	–	–	–
Head and neck squam cell carcinoma	–	✓✓	–	–	–
Kidney chromophobe	✓✓	✓✓	–	✓✓	–
Kidney renal clear cell carcinoma	–	✓✓	–	–	–
Kidney renal papillary cell carcinoma	✓✓	✓✓	–	✓✓	–
Acute myeloid leukemia	–	–	–	✓✓	–
Brain lower grade glioma	–	–	–	–	–
Liver hepatocellular carcinoma	–	–	✓✓	✓	–
Lung adenocarcinoma	–	–	✓✓	✓	–
Lung squamous cell carcinoma	–	✓✓	✓✓	✓	✓✓
Ovarian serous cystadenocarcinoma	–	–	✓✓	–	–
Pancreatic adenocarcinoma	✓	–	–	✓	–
Pheochromocytoma and paraganglioma	–	–	✓	–	–
Prostate adenocarcinoma	–	✓	–	✓	–
Rectum adenocarcinoma	✓	✓	–	–	–
Sarcoma	✓	✓	–	–	–
Skin cutaneous melanoma	–	✓✓	–	✓✓	–
Stomach adenocarcinoma	–	–	–	✓✓	–
Testicular germ cell tumor	✓✓	✓	✓	–	–
Thyroid carcinoma	✓✓	✓	–	✓✓	–
Thymoma	–	–	–	✓	–
Uterine corpus endometrium carcinoma	–	✓✓	–	–	–
Uterine carcinosarcoma	–	✓✓	–	–	–