Figure 3.

Model based on early FVC changes at 6 months relative to baseline.

The curves illustrate the model for 4 different groups, and the marks are patient groups.

Group number 1, no neoadjuvant chemotherapy plus smokers* (□ patients were divided into 33 percentiles). The same is true for group 2, neoadjuvant chemotherapy and smokers* (□). Group 3, no chemotherapy and non-smokers^o (○) and group 4, chemotherapy and non-smokers^o (◊) are each divided into 2 tiles.

The model for FEV₁ changes is not illustrated, since it is the same model despite there is only two covariates having a significant effect on FEV₁ changes at 6 months.

*smokers were defined as people having smoked within the last 10 years.^o Non-smokers were defined as never smoker or former- smokers ≥10 years.