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. 2020 Jun 2;59(31):12785–12788. doi: 10.1002/anie.202004797

Scheme 6.

Scheme 6

Ring opening of the pyrrolidin‐2‐one ring by a Grignard reagent (PhMgBr) after protection of the nitrogen atom of 1 a with a tert‐butyloxycarbonyl (Boc) group: Synthesis of acyclic allene 9 via intermediate 8.