Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 27;2020:1232816. doi: 10.1155/2020/1232816

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Sarmistha Saha et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Analysis of M_(IFN-γ/LPS) macrophage endocytosis. Lupeol prevents the impairment of endocytosis induced by 7-keto-cholesterol (7KC) in primary M_(IFN-γ/LPS) macrophages. Human primary M_(IFN-γ/LPS) macrophages were incubated with lupeol (10, 25, and 50 μM) followed by stimulation with 7KC (15 μM) and then added with FITC-dextran. The cellular uptake was then analyzed by flow cytometry. Results are expressed as a percentage of positive cells (%) and mean fluorescence intensity (MFI) (mean ± SD; n = 3). P values were tested by one-way ANOVA. ^∗Untreated vs. lupeol; ^¶Untreated control vs. 7KC-treated group; °7KC-treated group vs. 7KC+lupeol treated groups.