Table 1.
Baseline characteristics of derivation and validation cohorts.
| Characteristic | Derivation cohort (n = 1273) | Validation cohort (n = 415) | P value |
|---|---|---|---|
| Age (mean ± SD) (years) | 48.09 ± 12.91 | 48.97 ± 13.54 | 0.232 |
| BMI (mean ± SD) (kg/m2) | 25.57 ± 3.29 | 25.55 ± 3.36 | 0.898 |
| FPG (mean ± SD) (mmol/L) | 5.23 ± 0.67 | 5.25 ± 0.68 | 0.623 |
| TC (mean ± SD) (mmol/L) | 4.97 ± 0.90 | 5.04 ± 0.88 | 0.159 |
| TG (mean ± SD) (mmol/L) | 1.92 ± 1.32 | 1.94 ± 1.33 | 0.774 |
| HDL-C (mean ± SD) (mmol/L) | 1.32 ± 0.29 | 1.28 ± 0.28 | 0.011 |
| LDL-C (mean ± SD) (mmol/L) | 2.86 ± 0.68 | 2.90 ± 0.69 | 0.263 |
| ALT (mean ± SD) (mmol/L) | 31.39 ± 23.75 | 32.25 ± 23.49 | 0.524 |
| AST (mean ± SD) (mmol/L) | 27.49 ± 12.31 | 28.02 ± 10.88 | 0.429 |
| BUN (mean ± SD) (mmol/L) | 4.92 ± 1.18 | 4.93 ± 1.22 | 0.936 |
| CCR (mean ± SD) (mmol/L) | 76.22 ± 14.99 | 75.72 ± 14.62 | 0.551 |
| Follow-up (mean ± SD) (days) | 1078.09 ± 320.10 | 1087.86 ± 324.96 | 0.591 |
| Gender (n, %) | 0.707 | ||
| Male | 995 (78.16%) | 328 (79.04%) | |
| Female | 278 (21.84%) | 87 (20.96%) | |
| Smoking status (n, %) | 0.173 | ||
| Current | 335 (26.32%) | 108 (26.02%) | |
| Ever | 72 (5.66%) | 14 (3.37%) | |
| Never | 866 (68.03%) | 293 (70.60%) | |
| Drinking status (n, %) | 0.896 | ||
| Current | 88 (6.91%) | 26 (6.27%) | |
| Ever | 265 (20.82%) | 88 (21.20%) | |
| Never | 920 (72.27%) | 301 (72.53%) | |
| Family history (n, %) | 0.486 | ||
| No | 1187 (93.24%) | 391 (94.22%) | |
| Yes | 86 (6.76%) | 24 (5.78%) | |
| Incident T2D (n, %) | 0.433 | ||
| No | 1192 (93.64%) | 393 (94.70%) | |
| Yes | 81 (6.36%) | 22 (5.30%) |
Data are shown as means + SD or no. (%). BMI: body mass index; FBG: fasting blood glucose; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; CCR: creatinine clearance; T2D: type 2 diabetes.