Table 2.
T2D risk prediction in patients with hypertension based on Cox proportional risk regression model.
| Univariate analysis | P value | Multivariate analysis | P value | |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | |||
| Age | 1.04 (1.03, 1.06) | <0.0001 | 1.04 (1.02, 1.06) | 0.0009 |
| Gender | ||||
| Male | Reference | |||
| Female | 0.47 (0.25, 0.89) | NS | ||
| BMI | 1.13 (1.07, 1.20) | <0.0001 | 1.14 (1.05, 1.23) | 0.0016 |
| FPG | 6.60 (4.95, 8.81) | <0.0001 | 6.21 (4.28, 8.99) | <0.0001 |
| TC | 1.28 (1.04, 1.57) | 0.0203 | 1.26 (1.07, 1.53) | 0.0188 |
| TG | 1.29 (1.20, 1.39) | <0.0001 | 1.05 (0.86, 1.28) | NS |
| HDL-C | 0.29 (0.15, 0.57) | 0.0003 | 0.93 (0.33, 2.57) | NS |
| LDL-C | 1.17 (0.85, 1.60) | NS | ||
| ALT | 1.00 (1.00, 1.01) | NS | ||
| AST | 1.01 (1.00, 1.02) | NS | ||
| BUN | 1.13 (0.94, 1.36) | NS | ||
| CCR | 0.99 (0.97, 1.00) | 0.0458 | 1.00 (0.98, 1.02) | NS |
| Smoking status | ||||
| Current | Reference | Reference | ||
| Ever | 0.62 (0.27, 1.47) | NS | 0.49 (0.20, 1.18) | NS |
| Never | 0.32 (0.21, 0.51) | <0.0001 | 0.95 (0.44, 2.06) | NS |
| Drinking status | ||||
| Current | Reference | Reference | ||
| Ever | 0.17 (0.10, 0.29) | <0.0001 | 0.49 (0.20, 1.18) | NS |
| Never | 0.16 (0.08, 0.32) | <0.0001 | 0.95 (0.44, 2.06) | NS |
| Family history | ||||
| No | Reference | Reference | ||
| Yes | 3.79 (2.33, 6.15) | <0.0001 | 1.63 (0.82, 3.23) | NS |
T2D: type 2 diabetes; BMI: body mass index; FBG: fasting blood glucose; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; CCR: creatinine clearance; OR: odds ratio; CI: confidence interval; NS: no significance.