Table 1.
Correlation between SNORA71A expression and clinicopathological features in HCC patients.
Characteristics | Total | SNORA71A expression | P value | |
---|---|---|---|---|
Low (n = 66) | High (n = 66) | |||
Age, ys | 0.138 | |||
<60 | 85 | 46 (0.697) | 39 (0.591) | |
≥60 | 47 | 20 (0.303) | 27 (0.409) | |
Gender | 0.212 | |||
Female | 16 | 6 (0.091) | 10 (0.152) | |
Male | 116 | 60 (0.909) | 56 (0.848) | |
Hepatitis B | 0.310 | |||
Positive | 113 | 58 (0.879) | 11 (0.167) | |
Negative | 19 | 8 (0.121) | 55 (0.833) | |
Cirrhosis | 0.361 | |||
Present | 79 | 38 (0.576) | 41 (0.621) | |
Absent | 53 | 28 (0.424) | 25 (0.379) | |
AFP (ng/l) | 0.429 | |||
<400 | 82 | 42 (0.636) | 40 (0.606) | |
≥400 | 50 | 24 (0.364) | 26 (0.394) | |
Tumor diameter | 0.005∗ | |||
<5 cm | 34 | 10 (0.152) | 24 (0.364) | |
≥5 cm | 98 | 56 (0.848) | 42 (0.636) | |
Multiple lesions | 0.017∗ | |||
Present | 22 | 16 (0.242) | 6 (0.091) | |
Absent | 110 | 50 (0.758) | 60 (0.909) | |
Vessel carcinoma embolus | 0.160 | |||
Present | 34 | 20 (0.303) | 14 (0.212) | |
Absent | 98 | 46 (0.697) | 52 (0.788) | |
Microvascular invasion | 0.500 | |||
Present | 7 | 4 (0.061) | 3 (0.045) | |
Absent | 125 | 62 (0.939) | 63 (0.955) | |
Capsular invasion | 0.015∗ | |||
Present | 49 | 31 (0.470) | 18 (0.273) | |
Absent | 83 | 35 (0.530) | 48 (0.727) | |
Differentiation | 0.027∗ | |||
Low | 70 | 41 (0.621) | 29 (0.439) | |
High/moderate | 62 | 25 (0.379) | 37 (0.561) | |
TNM stage | 0.004∗ | |||
I~II | 91 | 38 (0.576) | 53 (0.803) | |
III~IV | 41 | 28 (0.424) | 13 (0.197) |
AFP = alpha fetal protein; TNM = tumor-node-metastasis; ∗P < 0.05; values are mean ± standard deviation or n (%).