Table 2.
Comparison of Optical Coherence Tomography (OCT) Parameters Between Alzheimer’s Disease (AD) Patients and Healthy Controls
| OCT Parameters | AD (54 Eyes) | Controls (57 Eyes) | Adjusted P-value | ||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| RNFL (µm) | |||||
| Mean thickness | 85.24 | 8.73 | 90.68 | 10.57 | 0.014 |
| Superior | 101.06 | 16.37 | 109.74 | 18.41 | 0.033 |
| Temporal | 64.39 | 9.671 | 68.74 | 12.17 | 0.075 |
| Inferior | 109.41 | 16.64 | 114.75 | 18.68 | 0.117 |
| Nasal | 66.00 | 8.57 | 69.60 | 7.65 | 0.063 |
| GCL-IPL (µm) | |||||
| Mean thickness | 68.81 | 15.52 | 76.42 | 11.69 | 0.014 |
| Superotemporal | 67.85 | 17.96 | 74.98 | 15.08 | 0.067 |
| Inferotemporal | 70.07 | 14.69 | 76.11 | 11.15 | 0.024 |
| Inferior | 67.49 | 16.24 | 74.23 | 11.51 | 0.018 |
| Inferonasal | 67.06 | 16.68 | 76.25 | 11.98 | 0.004 |
| Superonasal | 70.65 | 16.53 | 79.09 | 15.67 | 0.014 |
| Superior | 69.69 | 18.35 | 79.02 | 16.52 | 0.009 |
Notes: Bold values indicate statistically significant at adjusted P-value < 0.05.
Abbreviations: SD, standard deviation; RNFL, retinal nerve fiber layer; GCL-IPL, ganglion cell layer and inner plexiform layer.