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. 2020 Oct 6;17(10):e1003360. doi: 10.1371/journal.pmed.1003360

Table 3. Multivariable logistic regression of poor functional outcome (n = 21,886).

Variable Analysis with RT and SH Analysis with TPT
Adjusted OR (95% CI) p-Value Adjusted OR (95% CI) p-Value
Age 1.02 (1.02–1.03) <0.001 1.02 (1.02–1.03) <0.001
Sex
Female Reference Reference
Male 0.93 (0.82–1.05) 0.215 0.93 (0.82–1.04) 0.208
Mechanism of injury
Non-penetrating Reference Reference
Penetrating 0.15 (0.07–0.29) <0.001 0.15 (0.07–0.29) <0.001
Type of injury
No TBI Reference Reference
Mixed TBI 0.79 (0.68–0.93) 0.003 0.79 (0.68–0.92) 0.003
Isolated TBI 0.44 (0.37–0.53) <0.001 0.44 (0.37–0.53) <0.001
ISS ≥ 16 4.77 (4.03–5.66) <0.001 4.73 (3.99–5.61) <0.001
RTS < 7 7.74 (6.38–9.38) <0.001 7.79 (6.42–9.44) <0.001
Prehospital rescue airway* 1.88 (0.59–6.04) 0.288 1.88 (0.59–6.01) 0.290
Prehospital IV/IO access 3.63 (3.01–4.38) <0.001 3.61 (2.99–4.35) <0.001
RT (per 10 min) 1.06 (1.04–1.08) <0.001 NA NA
SH (per 10 min) 1.05 (1.01–1.08) 0.007 NA NA
TPT (per 10 min) NA NA 1.06 (1.04–1.08) <0.001

TPT was put in the multivariable logistic regression separately from RT and SH due to their strong collinearity.

*Rescue airway includes prehospital supraglottic airway and endotracheal tube insertion.

CI, confidence interval; IO, intraosseous line; ISS, Injury Severity Score; IV, intravenous line; NA, not applicable; OR, odds ratio; RTS, Revised Trauma Score; TBI, traumatic brain injury; TPT, total prehospital time.