Fig. 2.

BCG’s consensus gene signature (BCG-CGS) and highly enriched pathways. (a) A heat map of the log₂FC of the gene expression for differentially expressed genes representing BCG’s consensus gene signature. Upregulated genes have positive log₂FC denoted in red color, and down regulated genes have negative values for log₂FC denoted in blue color. (b) Core network for BCG-CGS showing highly connected genes in BCG-CGS, deleting all singleton genes. Nodes are color-coded using a split pie chart coloring scheme indicating pathway/gene set contribution to each node from the top 5 most enriched pathways/gene lists. All details about pathway/gene set ID are found in Table S2 (Supporting Information).