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. 2020 Oct 2;12:9435–9448. doi: 10.2147/CMAR.S272478

Figure 2.

Figure 2

Inhibition of hsa_circ_0084927 decreased the malignancy of CC cells. (A and B) The expression of hsa_circ_0084927 in Hela and SiHa cells after si-circRNA#1, si-circRNA#2, si-circRNA#3, or si-NC transfection was assessed by qRT-PCR. (C-P) Hela and SiHa cells were transfected with si-circRNA#1, si-circRNA#2, or si-NC. (C-M) The proliferation, colony formation, cell cycle progression, apoptosis, migration, and invasion of Hela and SiHa cells were determined with CCK-8, plate clone, flow cytometry, or transwell assays. (N-P) The levels of cyclin D1, c-caspase 3, MMP-2, and MMP-9 in Hela and SiHa cells were measured by Western blotting. *P < 0.05.