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. 2020 Oct 2;12:9435–9448. doi: 10.2147/CMAR.S272478

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© 2020 Shi et al.

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Hsa_circ_0084927 regulated the malignancy of CC cells through miR-634. (A-L) Hela and SiHa cells were transfected with si-NC, si-circRNA#1, si-circRNA#1+NC inhibitor, or si-circRNA#1+miR-634 inhibitor. (A and B) Expression of miR-634 in Hela and SiHa cells were examined with qRT-PCR. (C-J) CCK-8, plate clone, flow cytometry, and transwell assays were performed to determine the proliferation, colony formation, cell cycle progression, apoptosis, migration, or invasion of Hela and SiHa cells. (K and L) The levels of cyclin D1, c-caspase 3, MMP-2, and MMP-9 in Hela and SiHa cells were measured with Western blotting. *P < 0.05.