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. 2020 Oct 2;14:4085–4099. doi: 10.2147/DDDT.S270185

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© 2020 Cheng et al.

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Pica induced by cisplatin. Measurements in treated rats over time: (A) Kaolin consumption, (B) Food intake, (C) Body weight.

Notes: Values are expressed as mean ± SEM (n = 8). *P < 0.05, **P < 0.01, ***P < 0.01, compared to the control group; ^##P < 0.01, compared to the cisplatin model group. t=0, i.p. 6 mg/kg cisplatin.

Abbreviations: Con, normal control group; G-con, the [6]-gingerol control group; O-con, the ondansetron control group; Model, the cisplatin model group; O-treated, the ondansetron-treated model group; GH-treated, the high dosage of [6]-gingerol-treated model group; GL-treated, the low dosage of [6]-gingerol-treated model group.