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Impact Of Using Different FPER On Positive Predictive Values
| Called by assay | ||||||
|---|---|---|---|---|---|---|
| Pos. | Neg. | Total | ||||
| True | Pos. | 47,500 | 2500 | 50,000 | 95.00% | (Sensitivity or 1-FNER) |
| Neg. | 47,500 | 902,500 | 950,000 | 95.00% | (Specificity or 1-FPER) | |
| Total | 95,000 | 905,000 | 1,000,000 | |||
| 50.00% | 99.72% | 5.00% | ||||
| (PPV) | (NPV) | (Prevalence) | ||||
Cut point set with a 5% FPER (95% specificity). (Assuming 95% sensitivity and 5% antibody prevalence in the general population). A population size of 1 million is assumed for illustration
