Table 2.
Characteristics of convalescent plasma donors
| Donors | |||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | |
| Blood products coding | 399 | 400 | 397 | 933 | 395 | 703 | 701 |
| Centers | 1 | 1 | 1 | 2 | 1 | 3 | 3 |
| Sex | Male | Female | Male | Male | Female | Male | Male |
| Age | 26 | 49 | 39 | 41 | 47 | 34 | 43 |
| Donated plasma volume, mL | 400 | 400 | 400 | 300 | 400 | 400 | 400 |
| Blood type | A | A | A | A | B | A | B |
| Clinical classification | Mild | Moderate | Mild | Mild | Moderate | Moderate | Moderate |
| Comorbidities | None | None | None | None | None | None | None |
| Estimated incubation period, d | – | 20 | 3 | – | 3 | 9 | 6 |
| Days of plasma donation from symptom onset | 16 | 19 | 30 | 30 | 33 | 19 | 22 |
| Anti-SARS-CoV-2 specific IgM MCLIA titer | <1:50 | 1:50 | <1:50 | 1:320 | <1:50 | 1:50 | 1:50 |
| Anti-SARS-CoV-2 specific IgG MCLIA titer | 1:160 | 1:160 | 1:320 | 1:1280 | 1:1280 | 1:160 | 1:1280 |
| Anti-S-RBD specific IgG ELISA titer | 1:640 | 1:640 | 1:1280 | 1:2560 | 1:2560 | 1:1280 | 1:2560 |
| Anti-NP specific IgG ELISA titer | 1:640 | 1:320 | 1:1280 | 1:2560 | 1:2560 | 1:2560 | 1:5120 |
| IT50 | 1:6 | 1:3 | 1:74 | 1:33 | 1:12 | 1:17 | 1:20 |
| NAT50 | 1:320 | 1:255 | 1:312 | 1:1529 | 1:852 | 1:460 | 1:1576 |
MCLIA magnetic chemiluminescence enzyme immunoassay, ELISA enzyme-linked immunosorbent assay, S-RBD receptor binding domains of spike protein, NP nucleoprotein, IT50 inhibitory titer which was calculated with the dilution of plasma that inhibits 50% RBD-Fc binding to receptor ACE2, NAT50 neutralizing antibody titer which was calculated with the highest dilution of plasma that resulted in a 50% reduction of virus infection
Center 1–3 were Chongqing Public Health Medical Center, Affiliated Hospital of North Sichuan Medical College, and Chongqing Three Gorges Central Hospital, respectively