Table 4.
Correlation between muscle function outcome and quality of life in patients with Cushing’s syndrome in remission
| Time Points | Muscle Function | QoL Questionnaire | n | P-value | Spearman’s Coefficient |
|---|---|---|---|---|---|
| Baseline | CRT | CushingQoL | 53 | 0.030 | -0.298 |
| SF-36 PCS | 57 | 0.002 | -0.410 | ||
| 6 months | CRT | CushingQoL | 39 | 0.042 | -0.327 |
| SF-36 PCS | 42 | 0.007 | -0.413 | ||
| 1 y | CRT | SF-36 PCS | 30 | ≤0.001 | -0.626 |
| 2 y | CRT | CushingQoL | 21 | ≤0.001 | -0.714 |
| SF-36 PCS | 22 | ≤0.001 | -0.668 | ||
| SF-36 MCS | 22 | 0.013 | -0.522 | ||
| 3 y | Grip strength | CushingQoL | 17 | 0.050 | 0.480 |
| 4 y | Grip strength | CushingQoL | 10 | 0.029 | 0.685 |
| CRT | CushingQoL | 10 | 0.010 | -0.766 | |
| SF-36 PCS | 11 | ≤0.001 | -0.834 | ||
| SF-36 MCS | 11 | 0.010 | -0.737 |
Baseline and follow-up assessments before and after successful treatment. Worse muscle function in CRT corresponds to higher readings, while worse muscle function in grip strength corresponds to lower readings. Correlations were performed by Spearman’s correlation analysis. Bold P-values indicate statistical significance.
Abbreviations: CRT, chair rising test; CushingQoL, Cushing’s quality of life; QoL, quality of life; SF-36 MCS = Short Form 36 Mental Component Summary; SF-36 PCS, Short Form 36 Physical Component Summary; y, year.