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. 2020 Sep 1;95(9):e1267–e1284. doi: 10.1212/WNL.0000000000010404

Figure 1. Heat map depicting, by subgroup, the relative degree of α-synuclein (α-Syn) positivity.

Figure 1

α-Syn positivity across (A) each tissue type, as defined by the number of positive slides; and (B) each biofluid, as defined using quartile scores. For CSF and serum α-Syn, rank values in the lower quartile (i.e., the lowest 25% of values) were defined as most indicative of Parkinson disease (PD), whereas for saliva, plasma, and whole blood (WB) α-Syn, rank values in the upper quartile (i.e., the highest 25% of values) were defined as most indicative of PD. For each panel, participants are sorted by subgroup in order from lowest-to-highest average tissue positivity; accordingly, each given column across the 2 panels corresponds to the same participant. PC = paravertebral cervical; SMG = submandibular gland; T = thigh.