Skip to main content
. 2020 Sep 1;95(9):e1244–e1256. doi: 10.1212/WNL.0000000000010154

Figure 3. RNS System long term clinical response.

Figure 3

Plot showing the median percent reduction ± IQR in seizure frequency for the last 6 months of each year in the long-term treatment study (years 3 through 9 of treatment) compared to baseline for the 91-day minimum diary requirement population, the constant cohort population, and the last observation carried forward (LOCF) population. (A) Median percent reduction ± interquartile range (IQR) over time. (B) Individual changes in clinical seizure frequency. Changes in clinical seizure frequency during the last 6 months of follow-up before the year 9 visit for each participant who had at least 91 days of seizure diary data. Negative values indicate a seizure frequency reduction compared with baseline. (C) Bar graph showing the percent of all participants (All) and participants with onsets in the mesial temporal lobe (MTL) or neocortex (Neo) with at least 1 period of seizure freedom lasting at least 3, 6, and 12 months.