Table 2.
Allele frequencies of 9 SNPs in the human SHC3 gene between schizophrenia patients and controls
| rs code | Subjects | Allele and | frequency* | χ2 p (p†) | OR (95% CI) |
|---|---|---|---|---|---|
| A | G | ||||
| rs3812501 | Case | 269 (0.189) | 1,151 (0.811) | χ2=0.386 | 1.054 (0.893–1.244) |
| Control | 477 (0.182) | 2,151 (0.818) | p=0.535 | ||
| A | G | ||||
| rs2316280 | Case | 53 (0.037) | 1,367 (0.963) | χ2=5.844 | 0.674 (0.488–0.930) |
| Control | 143 (0.054) | 2,485 (0.946) | p=0.016‡ | ||
| A | G | ||||
| rs4877041 | Case | 1,352 (0.952) | 68 (0.048) | χ2=5.792 | 0.673 (0.486–0.931) |
| Control | 2,542 (0.967) | 86 (0.033) | p=0.016‡ | ||
| A | C | ||||
| rs7021743 | Case | 1,398 (0.985) | 22 (0.015) | χ2=13.215 | 0.291 (0.144–0.591) |
| Control | 2,616 (0.995) | 12 (0.005) | p=0.0003 (0.0027)‡ | ||
| G | T | ||||
| rs944485 | Case | 1,334 (0.939) | 86 (0.061) | χ2=6.687 | 0.684 (0.512–0.914) |
| Control | 2,517 (0.958) | 111 (0.042) | p=0.010‡ | ||
| C | T | ||||
| rs1547696 | Case | 1,372 (0.966) | 48 (0.034) | χ2=0.867 | 0.840 (0.581–1.213) |
| Control | 2,553 (0.971) | 75 (0.029) | p=0.352 | ||
| A | G | ||||
| rs4876968 | Case | 19 (0.013) | 1,401 (0.987) | χ2=0.049 | 1.066 (0.604–1.882) |
| Control | 33 (0.013) | 2,595 (0.987) | p=0.824 | ||
| A | G | ||||
| rs1556384 | Case | 29 (0.020) | 1,391 (0.980) | χ2=1.489 | 1.349 (0.833–2.185) |
| Control | 40 (0.015) | 2,588 (0.985) | p=0.222 | ||
| C | T | ||||
| rs4534195 | Case | 51 (0.036) | 1,369 (0.964) | χ2=1.485 | 1.251 (0.872–1.794) |
| Control | 76 (0.029) | 2,552 (0.971) | p=0.223 |
*
frequencies are shown in parenthesis,
†
p value after the strict Bonferroni correction,
‡
significant p values (p<0.05)