Table 2. Hepatic lipid profile in control and experimental groups of rats.
Control | HFD | HFD + SIM (20 mg/kg) | HFD + PCA50 mg/kg | HFD + PCA100 mg/kg | |
---|---|---|---|---|---|
Hepatic triglycerides | 4.24 3 ± 0.58 | 7.57 ± 0.23 a) | 4.02 ± 0.42 b) | 5.41 ± 0.40 b) | 4.81 ± 0.29 b) |
Hepatic total cholesterol | 6.57 ± 0.69 | 16.37 ± 0.55 a) | 7.87 ± 0.68 b) | 12.56 ± 1.2 b) | 11.32 ± 0.49 b) |
Values are expressed as mean ± SEM (mean of six determinations). PCA: protocatechuic acid. Control group; HFD represents the group fed with high fat and fructose diet; SIM represents simvastatin; PCA50 mg/kg represents protocatechuic acid at 50 mg/kg and PCA100 mg/kg represents protocatechuic acid at 100 mg/kg. a) and b) indicate significant differences compared to the values of Control and HFD groups, respectively at P<0.05.