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. 2020 Sep 23;10:558339. doi: 10.3389/fonc.2020.558339

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Copyright © 2020 Wang, Zhang, Xu, Zhang, Pan, Zhong, Zhang, Yin, Yao, Wu, Li, Liu, Xu and Niu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MI-2 induced apoptosis of T-ALL cells in a dose-dependent manner. (A) The effect of MI-2 on cell apoptosis was analyzed by FACS. (B,C) CCRF and MOLT-4 were plated with the indicated concentration of MI-2 for 12 h. Caspase-9 and caspase-3/7 activity were assessed according to the manufacturer’s protocol. (D,E) Representative images of apoptosis-related protein were shown. **P < 0.01.