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HLA-B*1502 and oxcarbazepine induced Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN).
| Article | Population | Description | Sensitivity | Specificity | PPV | NPV | Incidencei,iii | NNG | Frequency carriers in population (%) |
|---|---|---|---|---|---|---|---|---|---|
| Chen et al. (2017) | Taiwan Han Chinese | 50 cADR cases (20 SJS-TEN, 6 DRESS, 22 MPE, 2 BDFE) + 101 controls | 0.706 | 0.921 | 0.0073 | 0.9997 | 0.000826 | 1715 | 8.8 (Taiwan Han Chinese) (McCabe et al., 2020) |
