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. 2020 Sep 23;10:539805. doi: 10.3389/fonc.2020.539805

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Copyright © 2020 Zhou, Gao, Hua and Ji.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Recruitment of EZH2 by BLACAT1 to the promoter region from EZH2 to inhibit the expression of CDKN1C. (A) Detection of H3K27me3 enrichment in CDKN1C promoter by ChIP experiment. (B) Detection of CDKN1C expression in PC cells by western blot. (C) Detection of H3K27me3 enrichment in CDKN1C promoter by ChIP experiment. (D) Detection of CDKN1C expression after EZH2 knockdown in PC cells by western blot. Data were expressed as mean ± SD, unpaired Student’s t-test, n = 3, *P < 0.05. *Compared with sh-EZH2 NC group, P < 0.05; ^#compared with oe-NC group, P < 0.05.