Table 1.
Baseline characteristics by AF status and treatment allocation.
|
AF |
No AF |
|||
|---|---|---|---|---|
| Characteristic | ControlMean ± SD (N)[Median] (IQR) OR % (n/N) | EVTMean ± SD (N) [Median] (IQR)OR % (n/N) | ControlMean ± SD (N)[Median] (IQR)OR % (n/N) | EVTMean ± SD (N)[Median] (IQR)OR % (n/N) |
| Age (years) | 72.8 ± 9.4 (223)[74.0] (67.0, 79.0) | 72.8 ± 10.1 (224) [73.0] (67.0, 80.1) |
63.6 ± 13.6 (459) [64.7] (55.0, 74.0) |
63.1 ± 13.7 (443) [63.0] (54.0, 74.0) |
| Female gender | 49.8% (111/223) | 47.8% (107/224) | 44.8% (206/460) | 49.0% (217/443) |
| NIHSS at baseline | 16.8 ± 5.4 (223) [17.0] (14.0, 20.5) |
17.5 ± 4.8 (223) [18.0] (14.5, 21.0) |
16.9 ± 5.7 (457) [17.0] (13.0, 21.0) |
16.5 ± 5.2 (440) [17.0] (13.0, 20.0) |
| tPA delivered | 79.4% (177/223) | 73.2% (164/224) | 92.0% (424/461) | 89.2% (395/443) |
| Diabetes mellitus | 17.9% (40/223) | 21.0% (47/224) | 17.6% (81/461) | 15.1% (67/443) |
| Hypertension | 74.9% (167/223) | 68.8% (154/224) | 51.6% (238/461) | 48.5% (215/443) |
| ASPECTS at baseline | 8.1 ± 1.7 (219) [8.0] (7.0, 9.0) |
8.0 ± 1.7 (222) [8.0] (7.0, 9.0) |
7.6 ± 1.9 (452) [8.0] (7.0, 9.0) |
7.7 ± 1.7 (439) [8.0] (7.0, 9.0) |
| Occlusion location | ||||
| Not available | 7.2% (16/223) | 6.3% (14/224) | 5.6% (26/461) | 4.7% (21/443) |
| ICA | 24.2% (54/223) | 27.2% (61/224) | 29.3% (135/461) | 27.8% (123/443) |
| M1 | 61.0% (136/223) | 55.8% (125/224) | 55.7% (257/461) | 58.5% (259/443) |
| M2 | 7.6% (17/223) | 10.7% (24/224) | 9.3% (43/461) | 8.8% (39/443) |
| Other | 0.0% (0/223) | 0.0% (0/224) | 0.0% (0/461) | 0.2% (1/443) |
| Onset of tPA | 125.0 ± 66.4 (178) [110.0] (80.0, 147.8) |
115.7 ± 50.8 (162) [105.0] (75.3, 139.3) |
116.1 ± 60.9 (424) [100.0] (75.0, 145.0) |
111.5 ± 47.3 (395) [102.0] (75.0, 135.0) |
| Onset of randomisation | 213.4 ± 96.1 (223) [196.0] (139.0, 277.0) |
212.7 ± 104.9 (224) [191.0] (137.8, 257.5) |
208.4 ± 88.7 (458) [191.5] (141.3, 264.0) |
210.4 ± 99.3 (441) [193.0] (142.0, 253.0) |
AF: atrial fibrillation; NIHSS: National Institutes of Health Stroke Scale; tPA: tissue plasminogen activator; ASPECTS: Alberta Stroke Program Early CT Score; ICA: internal carotid artery; SD: standard deviation; AF: atrial fibrillation; EVT: endovascular thrombectomy.