Table 2.

Primary outcome, secondary outcomes, and p-value for interaction by AF status and treatment allocation.

		Unadjusted value (95% CI)			Adjusted value (95% CI)
	Effect	AF	No AF	P inter-action	AF	No AF	P inter-action
mRS score at 90 days	cOR	2.10 (1.33, 3.30)	2.21 (1.66, 2.94)	0.848	2.39 (1.47, 3.88)	2.34 (1.66, 3.31)	0.581
mRS score of 0–2 at 90 days	OR	1.99 (1.32, 2.99)	2.50 (1.88, 3.31)	0.350	2.41 (1.50, 3.85)	2.64 (1.96, 3.56)	0.544
NIHSS at 24 h	Beta	–2.96 (−5.12, −0.80)	–3.50 (–4.58, –2.41)	0.729	–3.50 (–5.74, –1.26)	−3.68 (−5.82, −1.54)	0.686
sICH	OR	1.15 (0.40, 3.35)	1.01 (0.54, 1.90)	0.848	1.09 (0.36, 3.30)	1.04 (0.55, 1.96)	0.900
Mortality at 90 days	OR	0.76 (0.47, 1.23)	0.86 (0.53, 1.40)	0.812	0.69 (0.41, 1.17)	0.89 (0.55, 1.45)	0.536

Results are unadjusted and adjusted for age, NIHSS at baseline, IVT, localisation of occlusion and time from onset to randomisation.

mRS; modified Rankin scale; AF: atrial fibrillation; NIHSS: National Institutes of Health Stroke Scale; sICH: symptomatic intracranial hemorrhage.