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. 2020 Sep 23;11:548943. doi: 10.3389/fphys.2020.548943

FIGURE 1.

FIGURE 1

Defective autophagy in VSMCs induces p62 accumulation in the femoral artery. (A) Immunostaining for and quantification of Atg7 of femoral artery segments of Atg7+/+ SM22α-Cre+ (+/+) and Atg7F/F SM22α-Cre+ (F/F) mice (n = 5). Independent sample t-test. *p < 0.05 **p < 0.01. (B) Femoral artery media thickness was not affected by autophagy deficiency. (C) Western blot analyses of p62 in femoral artery segments of Atg7+/+ SM22α-Cre+ (+/+) and Atg7F/F SM22α-Cre+ (F/F) mice with quantification relatively expressed to β-actin (n = 4). Scalebar = 100 μM.