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. 2020 Oct 6;10:16594. doi: 10.1038/s41598-020-73803-9

Table 2.

Topographic extent of abnormalities of spectral domain optical coherence tomography.

Variables Total (N = 166) Foveal centre involveda Foveal centre not involved
All Only center Temporalb Nasalb Temporal and nasal All Temporal Nasal
IR hyporeflective cavities 121 (72.9) 111 (91.7) 42 (37.8) 25 (22.5) 6 (5.4) 38 (34.2) 10 (8.3) 4 (40.0) 6 (60.0)
OR hyporeflective cavities (above ELM) 56 (33.7) 40 (71.4) 14 (35.0) 16 (40.0) 0 (0) 10 (25.0) 15 (26.8) 13 (86.7) 2 (15.4)
OR hyporeflective cavities (below ELM) 52 (31.3) 50 (96.2) 37 (74.0) 9 (18.0) 0 (0) 4 (8.0) 2 (4.0) 2 (100) 0 (0)
Collapsing outer retinal layers 45 (27.1) 29 (64.4) 17 (58.6) 0 (0) 12 (41.4) 16 (35.6) 16 (100) 0 (0)
Disorganization of IR layers 52 (31.3) 31 (59.6) 24 (77.4) 0 (0) 7 (22.6) 21 (38.5) 21 (100) 0 (0)
ELM disruption 67 (40.4) 58 (86.6) 11 (19.0) 29 (50.0) 0 (0) 18 (31.0) 9 (13.4) 9 (100) 0 (0)
EZ disruption 87 (52.4) 79 (90.8) 27 (34.2) 34 (43.0) 0 (0) 18 (22.8) 8 (9.2) 8 (100) 0 (0)
IDZ disruption 94 (56.6) 88 (93.6) 34 (38.6) 35 (39.8) 0 (0) 19 (21.6) 6 (6.4) 6 (100) 0 (0)

Data are expressed as number (%).

ELM external limiting membrane, EZ ellipsoid zone, IDZ interdigitation zone, IR inner retinal, OR outer retinal.

aFoveal centre involvement was defined as abnormalities located within the foveal floor without the inner retinal layers or less than about 300–600 μm from the foveolar centre.

bThe nasal side and the temporal side of fovea were classified depending on the relative position to the foveolar centre.