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. 2020 Oct 6;10:16646. doi: 10.1038/s41598-020-73759-w

Table 2.

Comparison of the characteristics of TB patients between those in high-risk areas only for non-MDR-TB and those in high–risk areas for both MDR- and non-MDR-TB, Continental Portugal, 2000–2016.

Patient’s characteristics Total
n
High-risk areas for non-MDR-TB but not for MDR-TB High-risk areas for both MDR- and non-MDR-TB p-value
na IQR or % na IQR or %
Age (years)
Median (IQR) 32,114 42.0 25 40.0 24 < 0.001b
Gender
Female 32,114 4816 31.3 5793 34.6 < 0.001
Male 10,562 68.7 10,943 65.4
Country of origin
Foreign-born 32,077 1107 7.2 4266 25.5 < 0.001
Native 14,255 92.8 12,449 74.5
HIV status
Negative 32,114 13,508 87.8 13,240 79.1 < 0.001
Positive 1870 12.2 3496 20.9
Alcohol abusef
No 28970e 11,867 86.1 12,544 82.6 < 0.001
Yes 1911 13.9 2648 17.4
Injectable drug usef
No 29480e 12,655 89.8 12,891 83.7 < 0.001
Yes 1431 10.2 2503 16.3
Reclusionc
No 29152e 13,895 98.5 14,440 96.0 < 0.001
Yes 217 1.5 600 4.0
Community residenced
No 29005e 13,687 97.6 14,259 95.1 < 0.001
Yes 331 2.4 728 4.9
Homelessness
No 29136e 13,940 98.9 14,549 96.7 < 0.001
Yes 148 1.1 499 3.3
Diabetes
No 32,114 14,654 95.3 15,892 95.0 0.172
Yes 724 4.7 844 5.0
Silicosis
No 32,114 15,161 98.6 16,720 99.9 < 0.001
Yes 217 1.4 16 0.1
Previous TB treatment
No 32,114 13,844 90.0 14,631 87.4 < 0.001
Yes 1534 10.0 2105 12.6
Site of disease
Pulmonary 32011e 11,574 75.5 11,961 71.7 < 0.001
Extra-pulmonary 3752 24.5 4724 28.3

TB tuberculosis, MDR-TB multidrug-resistant tuberculosis, IQR interquartile range, HIV human immunodeficiency virus.

aNot applicable for age.

bMann–Whitney U-test.

cPrison confinement.

dSocial housing for people with socio-economic vulnerabilities.

eData missing for: country of origin (n = 37; 0.1%), alcohol abuse (n = 3144; 9.8%), injectable drug use (n = 2634; 8.2%), reclusion (n = 2962; 9.2%), community residence (n = 3109; 9.7%), homelessness (n = 2978; 9.3%), site of disease (n = 103; 0.3%).

fSelf-reported.