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. 2020 Oct 6;10:16581. doi: 10.1038/s41598-020-73644-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Scatterplot showing the distribution of 3081 AMPs according to outlier scores and hemolytic (HemoPI-1) consensus class probabilities. Changes in the outlier scores and probabilities are illustrated with different shades of blues. Selected 34 non-hemolytic AMPs (golden circles) with lowest outlier scores and hemolytic predictions. Darkest data points are 273 AMPs detected as outliers according to HemoPI-1 Average KNN with percentile outlier scores > 0.91. (b) Colour-coded antimicrobial peptide families (e.g. dermaseptins) from different source organisms.