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. 2020 Oct 7;371:m3503. doi: 10.1136/bmj.m3503

Table 2.

Prevalence of men with localised prostate cancer and of control men who reported incontinence, bowel problems, or impotence at 15 years by initial treatment

Condition and follow-up year Participant group (type of treatment or control) (No who reported condition/Total No in group (%))
AS/WW NSRP Non-NSRP EBRT/HDR ADT LDR Controls
Urinary incontinence*:
 Baseline 12/200 (6.0) 3/494 (0.6) 7/478 (1.5) 0/170 9/227 (4.0) 0/58 5/495 (1.0)
 15 years 6/53 (11.3) 35/192 (18.2) 38/141 (27.0) 6/43 (14.0) 5/45 (11.1) 1/25 (4.0) 0/103
Moderate or severe bowel problems†:
 Baseline 27/200 (13.5) 18/494 (3.6) 25/478 (5.2) 14/170 (8.2) 21/227 (9.3) 0/58 31/495 (6.3)
 15 years 6/53 (11.3) 12/192 (6.3) 4/141 (2.8) 6/43 (14.0) 8/45 (17.8) 0/25 2/103 (1.9)
Erectile dysfunction‡:
 Baseline 53/200 (26.5) 76/494 (15.4) 128/478 (26.8) 47/170 (27.6) 87/227 (38.3) 11/58 (19.0) 109/495 (22.0)
 15 years 33/53 (62.3) 144/192 (75.0) 117/141 (83.0) 34/43 (79.1) 34/45 (75.6) 18/25 (72.0) 44/103 (42.7)

ADT=androgen deprivation therapy with or without EBRT; AS/WW=active surveillance/watchful waiting; EBRT/HDR=external beam radiotherapy or high dose rate brachytherapy only (no androgen deprivation therapy); LDR=low dose rate brachytherapy; N/A=not available; non-NSRP=non-nerve sparing radical prostatectomy; NSRP=nerve sparing radical prostatectomy.

*

Incontinence is defined as needing to wear one or more pad per day owing to weak urinary control and frequent leakage.

Bowel problems are defined as participants’ responses to the question “Overall, how big a problem have your bowel habits been?” being either “moderate” or “big.”

Erectile dysfunction is defined as being unable to obtain an erection sufficient for penetrative intercourse.