Table 5.
Comparison of ADC histogram parameters of the two different ROIs between IDHwt gliomas and IDHmut gliomas.
| Values (×10−6 mm2/s) | IDHwt group, n = 16 | IDHmut group, n = 40 | Test values | p values |
|---|---|---|---|---|
| ADCmean1 | 1646.10 ± 402.18 | 1419.95 (1279.30, 1565.89) | -1.796b | 0.073 |
| ADCmean2 | 1368.54 ± 254.39 | 1341.13 (1242.53, 1547.90) | -0.109b | 0.913 |
| ADCmin1 | 518.50 ± 226.12 | 701.86 ± 123.14 | -3.067a | 0.006 |
| ADCmin2 | 485.38 ± 195.34 | 708.38 ± 132.54 | -4196a | <0.001 |
| P5 ADC1 | 972.53 ± 207.95 | 1010.00 (929.86, 1094.88) | -0.852b | 0.394 |
| P5 ADC2 | 880.19 ± 168.79 | 1009.00 (913.75, 1076.75) | -2.648b | 0.008 |
| P10 ADC1 | 1066.38 ± 239.79 | 1073.25 (987.88, 1161.63) | -0.381b | 0.703 |
| P10 ADC2 | 966.75 ± 184.50 | 1069.50 (970.75, 1173.75) | -1.904b | 0.057 |
| P25 ADC1 | 1281.41 ± 306.36 | 1205.75 (1104.88, 1336.38) | -0.689b | 0.491 |
| P25 ADC2 | 1142.50 ± 220.39 | 1178.50 (1081.50, 1331.75) | -1.904b | 0.301 |
| P50 ADC1 | 1606.94 ± 442.95 | 1352.75 (1255.63, 1586.38) | -1.560b | 0.119 |
| P50 ADC2 | 1368.63 ± 267.23 | 1320.50 (1225.00, 1547.25) | -01.109b | 0.913 |
| P75 ADC1 | 2022.41 ± 580.95 | 1586.50 (1411.63, 1764.75) | -2.385b | 0.017 |
| P75 ADC2 | 1593.25 ± 304.42 | 1481.50 (1356.50, 1749.00) | -0.580b | 0.562 |
| P90 ADC1 | 2298.56 ± 620.70 | 1815.25 (1615.50, 2003.50) | -2.430b | 0.015 |
| P90 ADC2 | 1767.56 ± 331.19 | 1687.38 ± 264.32 | 0.953a | 0.345 |
| P95 ADC1 | 2403.84 ± 609.61 | 2002.78 ± 417.24 | 2.415a | 0.025 |
| P95 ADC2 | 1864.00 ± 342.97 | 1768.46 ± 260.47 | 1.135a | 0.261 |
| ADCmax1 | 3606.75 ± 1159.31 | 2716.50 (2161.63, 3409.75) | -2.195b | 0.028 |
| ADCmax2 | 2450.25 ± 417.17 | 2308.40 ± 373.60 | 1.242a | 0.220 |
| ADCmode1 | 1616.19 ± 583.11 | 1285.00 (1139.50, 1619.25) | -1.324b | 0.185 |
| ADCmode2 | 1517.06 ± 533.69 | 1273.50 (1142.25, 1610.25) | -0.517b | 0.605 |
| Kurtosis1 | -0.527 (-1.027, 0.480) | 0.661 (-0.397, 2.273) | -2.721b | 0.007 |
| Kurtosis2 | −0.401 ± 0.429 | -0.126 (-0.374, 0.304) | -2.512b | 0.012 |
| Skewness1 | 0.434 ± 0.689 | 0.664 ± 0.831 | -0.979a | 0.332 |
| Skewness2 | 0.065 ± 0.310 | 0.198 ± 0.522 | -0.955a | 0.344 |
| StDev1 | 388.630 (343.670, 689.60) | 278.864 (217.080, 357.755) | -3.156b | 0.002 |
| StDev2 | 303.055 ± 72.511 | 231.352 ± 51.862 | 4.110a | <0.001 |
| Inhomogenity1 | 0.278 ± 0.069 | 0.190 (0.160, 0.231) | -3.347b | 0.001 |
| Inhomogenity2 | 0.220 ± 0.033 | 0.165 ± 0.025 | 6.048a | <0.001 |
| Range1 | 3087.31 ± 1130.76 | 1941.25 (1406.00, 2788.38) | -2.721b | 0.007 |
| Range2 | 1966.56 ± 389.39 | 1610.93 ± 406.61 | 2.991a | 0.004 |
| Entropy1 | 3.968 ± 0.224 | 3.950 ± 0.249 | 0.218a | 0.825 |
| Entropy2 | 4.082 ± 0.199 | 4.034 ± 0.203 | 0.798a | 0.428 |
1ROI-1; 2ROI-2; at value; bZ value.