Table 1.
Clinicopathologic characteristic of the 234 HNSCC patients included in the study: overall and by subtypes.
| Overall | Subtypes | ||||
|---|---|---|---|---|---|
| Variable | N (%) | Oropharynx | Hypopharynx | Larynx | Oral cavity |
| N (%) | N (%) | N (%) | N (%) | ||
| 234 (100) | 90 (38.5) | 63 (26.9) | 41 (17.5) | 40(17.1) | |
| Age (years ± SD) | 57.42 ± 6.9 | 59.46 ± 6.7 | 56.61 ± 8.1 | 58.34 ± 5.7 | 57.55 ± 6.9 |
| Sex | |||||
| Man | 209 (89.7) | 76 (36.4) | 59 (28.2) | 40 (19.1) | 34 (16.3) |
| Woman | 24 (10.3) | 14 (58.3) | 3 (12.5) | 1 (4.2) | 6 (25.0) |
| Unk | 1 | 0 | 1 | 0 | 0 |
| TNM | |||||
| III | 20 (8.7) | 11 (55.0) | 1 (5.0) | 4 (20.0) | 4 (20.0) |
| IVA | 165 (71.4) | 64 (38.8) | 43 (26.1) | 29 (17.6) | 29 (17.6) |
| IVB | 46 (19.9) | 15 (32.6) | 17 (37.0) | 8 (17.4) | 6 (13.0) |
| Unk | 3 | 0 | 2 | 0 | 1 |
| Grade | |||||
| Well differentiated | 32 (15.1) | 13 (40.6) | 8 (25.0) | 3 (9.4) | 8 (25.0) |
| Moderately differentiated | 102 (48.1) | 41 (40.2) | 15 (14.7) | 27 (26.5) | 19 (18.6) |
| Poorly differentiated | 78 (36.8) | 28 (35.9) | 32 (41.0) | 9 (11.5) | 9 (11.5) |
| Unk | 22 | 8 | 8 | 2 | 4 |
| Histology | |||||
| Keratinizing | 94 (48.0) | 40 (42.6) | 19 (20.2) | 13 (13.8) | 22 (23.4) |
| Non-keratinizing | 100 (51.0) | 36 (36.0) | 31 (31.0) | 25 (25.0) | 8 (8.0) |
| Undifferentiated | 2 (1.0) | 1 (50.0) | 0 (0) | 0 (0) | 1 (50.0) |
| Unk | 38 | 13 | 13 | 3 | 9 |
| HPV | |||||
| Positive | 13 (6.7) | 13 (100.0) | 0 (0) | 0 (0) | 0 (0) |
| Negative | 182 (93.3) | 63 (34.6) | 50 (27.5) | 38 (20.9) | 31 (17.0) |
| Unk | 39 | 14 | 13 | 3 | 9 |
TNM classification system stands for tumour, node and metastasis.
SD standard deviation, Unk unknown.