Table 4.
Association between mutational status and response after induction and randomization (final response), without VUS.
| Variable | Normal | Pathogenic | OR | 95% CI | p-value |
|---|---|---|---|---|---|
| N (%) | N (%) | ||||
| Response after induction | 37 (21.5) | 135 (78.5) | |||
| Complete | 5 (13.5) | 19 (14.1) | 0.954 | 0.330–2.753 | 0.931 |
| Partial/stabilization | 32 (86.5) | 116 (85.9) | |||
| Final response | 21 (17.9) | 96 (82.1) | |||
| Complete | 13 (61.9) | 61 (63.5) | 0.932 | 0.352–2.469 | 0.888 |
| Partial/stabilization | 8 (38.1) | 35 (36.5) |
p-value significant if p < 0.05 and size effect indicated by the odd ratio (OR) with 95% confidence interval (CI). 172 (73.5%) and 117 (50.0%) patients were evaluable after induction chemotherapy or randomization respectively.