Table 5.
Association between HPV status and response after induction and randomization (final response).
Variable | HPV-negative | HPV-positive | OR | 95% CI | p-value |
---|---|---|---|---|---|
N (%) | N (%) | ||||
Response after induction | 52 (80.0) | 13 (20.0) | |||
Complete | 7 (70.0) | 3 (30.0) | 0.519 | 0.114–2.362 | 0.396 |
Partial/stabilization | 45 (81.8) | 10 (18.2) | |||
Final response | 33 (78.6) | 9 (21.4) | |||
Complete | 19 (79.2) | 5 (20.8) | 1.086 | 0.246–4.793 | 0.914 |
Partial/stabilization | 14 (77.8) | 4 (22.2) |
p-value significant if p < 0.05 and size effect indicated by the odd ratio (OR) with 95% confidence interval (CI). From initial 76 oropharyngeal tumours with HPV determination, 65 (85.5%) of them were evaluable for response after induction and 42 (55.3%) for final response.