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. 2020 Aug 9;10(4):490–501. doi: 10.34172/apb.2020.061

Table 2. Overview of various injectable scaffolds uses in MI80 .

Scaffolds (Natural and synthetic) Material form Delivery factor
Alginate Hydrogel HGF, IGF-1; PDGF-BB, VEGF-A
Chitosan Hydrogel bFGF; FGF-2
Collagen Hydrogel N/A
Decellularized myocardial ECM Hydrogel N/A
Decellularized pericardial ECM Hydrogel bFGF; HGF
Dextran Microparticles HGF
Fibrin Hydrogel bFGF
Gelatin Microspheres bFGF; IGF-1, VEGF
Hyaluronic acid Hydrogel rTIMP-3
Keratin Hydrogel N/A
Matrigel Hydrogel N/A
PEG based Hydrogel VEGF; HGF, VEGF; HGF, IGF-1; EPO
PLGA based Microparticles, nanoparticles NRG-1, FGF-1; VEGF; IGF-1
PNIPAAm based Hydrogel bFGF
UPy Hydrogel HGF, IGF-1

bFGF: basic fibroblast growth factor; FGF: fibroblast growth factor; HGF: hepatocyte growth factor; IGF: insulin-like growth factor; MI: myocardial infarction; PDGF-BB: platelet-derived growth factor BB; PEG: polyethylene glycol; PLGA: poly(lactic-co-glycolic acid); PNIPAAm: poly(N-isopropylacrylamide); rTIMP: recombinant tissue inhibitor of matrix metalloproteinase-3; SDF-1: stromal cell-derived factor; UPy: ureidopyrimidinone; VEGF: vascular endothelial growth factor.