Table 1.
HbA1c parameters | Diabetic peripheral neuropathy diagnosis | |||||
---|---|---|---|---|---|---|
Clinical (NSS/NDS) n = 16 | Nerve conduction studies n = 14 | Clinical and NCS (Toronto criteria) n = 12 | ||||
Model 1* OR (95% CI) |
Model 2* OR (95% CI) |
Model 1* OR (95% CI) |
Model 2* OR (95% CI) |
Model 1* OR (95% CI) |
Model 2* OR (95% CI) |
|
HbA1c-SD | 3.65 (1.11–12.05)† | 3.77 (0.98–14.49) | 4.22 (1.04–17.24)† | 4.88 (0.83–28.57) | 10.41 (1.38–78.4)† | 13.44 (1.46–123.6)† |
Mean HbA1c | 2.21 (0.84–5.81) | 2.07 (0.72–5.95) | 12.35 (1.74–83.3)† | 10.10 (1.14–90.9)† | 4.99 (0.92–27.16) | 3.91 (0.83–18.34) |
HbA1c-CV | 2.75 (1.06–7.09)† | 2.75 (0.95–8.00) | 3.38 (1.04–10.99)† | 3.83 (0.83–17.86) | 6.57 (1.25–34.72)† | 8.47 (1.25–57.61)† |
Mean HbA1c | 3.26 (1.28–8.26)† | 3.08 (1.12–8.47)† | 20.0 (2.77–142.8)‡ | 16.67 (2.09–142.9)‡ | 10.79 (1.93–60.2)‡ | 8.59 (1.62–45.61)† |
NSS neuropathy symptoms score, NDS neuropathy disability score, NCS nerve conduction study, OR odds ratio, CI confidence interval
* Odds ratios were estimated for increments of 1 − SD in each HbA1c parameter (mean HbA1c 1.7%, HbA1c-SD 0.7% and HbA1c-CV 6.3), and adjusted for age and sex in Model 1 and further adjusted for BMI, presence of essential hypertension and of other microvascular complications in Model 2. †p < 0.05; ‡p < 0.01